Centennial

Five Great Mexican Restaurants in Centennial

Centennial diners enjoy some great options for mexican food

Tom Carroll

Tom Carroll

Aug 6, 2026

18 Comments

Centennial’s Mexican dining scene offers everything from traditional family recipes and sizzling molcajetes to street tacos, breakfast burritos and creative margaritas. Whether you’re planning a family dinner, a casual lunch or a lively night out, these five local restaurants are worth exploring.

 

1. Los Dos Potrillos

Los Dos Potrillos has grown from a family-owned neighborhood restaurant into one of the Denver area’s best-known destinations for traditional Mexican food. Its Centennial location serves generous portions in a colorful, energetic setting.

The extensive menu includes enchiladas, chile rellenos, fajitas, carnitas and combination plates. For a meal that makes an entrance, order one of the restaurant’s sizzling molcajetes, filled with grilled meats, shrimp, vegetables and flavorful sauce.

 

Try: Molcajete, carnitas or chile rellenos
Location: 8251 S. Holly St.
Phone: (720) 529-0299
Website: Los Dos Potrillos Centennial

 

2. El Karajo Mexican Restaurant

El Karajo is a family-owned restaurant serving an impressive variety of authentic Mexican dishes. Its broad menu makes it a good choice for groups, with options ranging from street tacos and tortas to seafood, enchiladas, fajitas and volcanic-stone molcajetes.

The restaurant also offers vegetarian and gluten-free selections, a full bar and weekday happy-hour specials. Centennial diners can choose between its Quebec Street and University Boulevard locations. El Karajo

 

Try: Molcajete, birria, carne asada or poblano enchiladas
Locations: 6600 S. Quebec St., Unit A, and 7592 S. University Blvd., Unit A-100
Website: El Karajo Mexican Restaurant

 

3. Tacos El Patrón

For a casual meal packed with authentic flavor, Tacos El Patrón is an excellent neighborhood choice. The restaurant specializes in Mexican street tacos and slow-roasted rotisserie chicken prepared with traditional seasonings.

Along with tacos and chicken, the menu includes burritos, quesadillas, sopes, gorditas and family-sized meals. Its combination of affordable prices, quick service and generous portions also makes it convenient for takeout or feeding a crowd. Tacos El Patrón

 

Try: Rotisserie chicken, street tacos or a smothered burrito
Location: 8283 S. Akron St., Suite 130
Phone: (303) 953-9576
Website: Tacos El Patrón

4. My Neighbor Felix

My Neighbor Felix brings a contemporary approach to Mexican dining. Described as a Pan-Mexican kitchen and bar, it draws inspiration from several regions of Mexico while pairing its food with a lively dining room, attractive patio and creative cocktail program.

The colorful atmosphere makes Felix especially well suited for date night, weekend brunch or a celebration with friends. Guests can choose from street tacos, enchiladas, shareable appetizers and a varied selection of margaritas.

 

Try: Street tacos, birria enchiladas or a house margarita
Location: 7209 S. Clinton St.
Phone: (720) 736-8616
Website: My Neighbor Felix Centennial

 

5. Little George’s Mexican Restaurant

Little George’s combines Mexican comfort food with the warmth of a neighborhood restaurant. The welcoming dining room, full bar and outdoor patio make it equally appealing for a casual lunch, family meal or relaxed evening out.

Breakfast lovers will find chilaquiles and breakfast burritos, while the regular menu features tacos, fajitas, chile rellenos, tamales and carne asada. Its current posted hours begin at 10 a.m. daily. Little George’s

 

Try: Chilaquiles, breakfast burrito, carne asada or chile relleno
Location: 7422 S. University Blvd.
Phone: (303) 284-3194
Website: Little George’s Mexican Restaurant

 

From the traditional favorites at Los Dos Potrillos to the street tacos at Tacos El Patrón and the modern atmosphere at My Neighbor Felix, these five restaurants demonstrate the variety of Mexican dining available right here in Centennial. Bring your appetite—and consider ordering something new on your next visit.

 

Menus, prices and hours may change. Check with each restaurant before visiting.

 

18 Comments

Join the conversation

  • LR
    Laura R.· Aug 6, 5:11 PM

    So happy there are finally good Mexican brunch options here. Chilaquiles at Little George’s are now on my weekend must-try list!

    • JL
      Josh L.· Aug 6, 6:54 PM

      Laura R.You’ll love them! Little George’s does a great breakfast. Their burritos are solid too if you want a backup plan.

  • SP
    Sharon P.· Aug 6, 3:28 PM

    Thanks for mentioning that menus and hours change! I showed up at one of these once and they were closed early. Always call ahead, folks.

    • TC
      Tom CarrollAuthor· Aug 6, 6:54 PM

      Thank you for reinforcing this tip! Restaurant hours can change, so it’s always smart to double-check before heading out.

  • RC
    Raul Chavez· Aug 6, 1:45 PM

    Honestly, I think Tacos El Patrón could use more seating. The food is solid but sometimes it’s tricky to grab a spot during lunch rush.

  • TS
    Tina S.· Aug 6, 12:02 PM

    I didn’t know Los Dos Potrillos started as a neighborhood spot, it always seems packed! The chile rellenos are my favorite in town.

    • EP
      Eduardo P.· Aug 6, 6:54 PM

      Tina S.Yeah, it’s wild how much it’s grown. The wait for a table on weekends is no joke, but I agree, their chile rellenos are worth it every time.

    • TC
      Tom CarrollAuthor· Aug 6, 6:54 PM

      Absolutely, Los Dos Potrillos really grew from humble beginnings, and their chile rellenos are a standout! Thanks for highlighting a classic dish.

  • KT
    Kim Tran· Aug 6, 10:18 AM

    We celebrated my son’s birthday at My Neighbor Felix last month, awesome food and super fun vibe. Highly recommend for groups!

  • D
    davidm_72· Aug 6, 8:35 AM

    Little George’s breakfast burrito is the best way to start the day. Big portions and friendly folks there every time I go.

    • TC
      Tom CarrollAuthor· Aug 6, 6:54 PM

      We're so glad you love Little George’s breakfast burrito, between the generous portions and the welcoming atmosphere, it's definitely a local morning favorite.

  • MJ
    Melissa J.· Aug 6, 6:52 AM

    I wish one of these places offered more vegan options. Looks like El Karajo has some, so maybe I’ll give it a try. Thanks for the tip!

    • CV
      Casey V.· Aug 6, 11:21 AM

      Melissa J.Let us know if you find anything else good and vegan nearby! Options are definitely limited, but El Karajo usually has a few solid choices.

  • JH
    Jorge H.· Aug 6, 5:09 AM

    Love seeing so many family-owned spots in the mix. Street tacos at El Patrón are my go-to late night craving. Fast, tasty, and cheap!

  • C
    Chris_D· Aug 6, 3:26 AM

    Glad to see My Neighbor Felix get a shoutout. Their margaritas are really fun, but I still go to Los Dos Potrillos for the molcajete. Can’t beat it.

    • TC
      Tom CarrollAuthor· Aug 6, 6:54 PM

      Thank you for sharing your favorites! It's great to hear you're enjoying both My Neighbor Felix’s spirited margaritas and the unforgettable molcajete at Los Dos Potrillos.

  • JB
    Jenny Bates· Aug 6, 1:43 AM

    I’ve been to El Karajo on Quebec and it never disappoints. Their poblano enchiladas are so good! Planning to try Little George’s next weekend.

    • AC
      Angela C.· Aug 6, 6:54 PM

      Jenny BatesI feel the same way about their tacos! Let us know what you think of Little George’s, I’ve heard their breakfast burrito is great too.

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